Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | CYP51A1 | Q16850 | 4/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16609252 | 0.94 | ADRB2 (0.43) | ADRB2BCHEACHECYP51A1 | |
| SCHEMBL16609243 | 0.83 | CYP51A1 (0.42) | CYP51A1TAAR1KDM4E | |
| SCHEMBL16609244 | 0.78 | TSHR (0.47) | — | |
| SCHEMBL9813896 | 0.72 | OPRK1 (0.51) | BCHECYP51A1TAAR1KDM4E | |
| SCHEMBL9641990 | 0.71 | KDM4E (0.54) | CYP51A1TAAR1KDM4E | |
| SCHEMBL28270197 | 0.69 | ALDH1A1 (0.70) | KDM4E | |
| SCHEMBL4167977 | 0.69 | ALDH1A1 (0.70) | KDM4E | |
| SCHEMBL16297292 | 0.68 | ALDH1A1 (0.67) | KDM4E | |
| SCHEMBL10775174 | 0.68 | ALDH1A1 (0.67) | KDM4E | |
| SCHEMBL6931598 | 0.68 | ALDH1A1 (0.67) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015044965-A1 | A PROCESS FOR PREPARATION OF MIRABEGRON AND ALPHA CRYSTALLINE FORM THEREOF | MEGAFINE PHARMA (P) LTD. (IN) | 2015-04-02 | — | — | WO | disclosed |