SCHEMBL16609302

SCHEMBL16609302

C/C(=N/N)c1ccc([S+]([O-])c2ccc(/C(C)=N\N)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 2/20 0.39
▸ CA2 P00918 5/20 0.33
▸ LMNA P02545 2/20 0.33
▸ POLB P06746 1/20 0.33
▸ CA1 P00915 4/20 0.31
▸ CA4 P22748 4/20 0.31
▸ CA9 Q16790 4/20 0.31
▸ METTL3 Q86U44 1/20 0.30
▸ CYP1A2 P05177 1/20 0.30
▸ CYP2C9 P11712 1/20 0.30
▸ CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18001172 0.88 FURIN (0.32) FURIN
SCHEMBL18015097 0.88 GAA (0.39) FURINCA2
SCHEMBL18001594 0.84 CA2 (0.32) CA2
SCHEMBL18015096 0.76 GAA (0.36) CA2LMNAPOLBCA1CA4
SCHEMBL18015095 0.76 GAA (0.43) FURINCA2
SCHEMBL15053148 0.73 CYP19A1 (0.50) FURINLMNAPOLB
SCHEMBL6846692 0.73 FURIN (0.44) FURINLMNACA9CYP1A2
SCHEMBL2704783 0.73 MEN1 (0.47) FURINLMNACYP1A2CYP2C9CYP2C19
SCHEMBL2067685 0.73 FURIN (0.44) FURINLMNACA9CYP1A2
SCHEMBL21164826 0.72 ALDH1A1 (0.37) LMNAPOLBMETTL3CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351662-B2 Degradable hydrazone curing agents and applications thereof ADESSO ADVANCED MATERIALS WUHU CO., LTD. (CN) 2019-07-16 — — US disclosed
US-20160264718-A1 DEGRADABLE HYDRAZONE CURING AGENTS AND APPLICATIONS THEREOF ADESSO ADVANCED MATERIALS WUXI CO., LTD. (CN) 2016-09-15 — — US disclosed
US-20160264718-A1 DEGRADABLE HYDRAZONE CURING AGENTS AND APPLICATIONS THEREOF ADESSO ADVANCED MATERIALS WUXI CO., LTD. (CN) 2016-09-15 — — US disclosed
US-20160229949-A1 DEGRADABLE HYDRAZONE CURING AGENTS AND APPLICATIONS THEREOF ADESSO ADVANCED MATERIALS WUXI CO., LTD. (CN) 2016-08-11 — — US disclosed
US-20160229949-A1 DEGRADABLE HYDRAZONE CURING AGENTS AND APPLICATIONS THEREOF ADESSO ADVANCED MATERIALS WUXI CO., LTD. (CN) 2016-08-11 — — US disclosed
WO-2015043462-A1 DEGRADABLE HYDRAZONE CURING AGENTS AND APPLICATIONS THEREOF ADESSO ADVANCED MATERIALS WUXI CO., LTD. (CN) 2015-04-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351662-B2 Degradable hydrazone curing agents and applications thereof EGLN2, EGLN3, P4HA1 FURIN 412/4885CA2 1218/4885LMNA 52/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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