SCHEMBL16610054

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18020584	0.90	PRSS1 (0.46)	SMN1; SMN2KMT2AMAPTPRSS1ACR
	SCHEMBL16610043	0.88	MAPT (0.55)	KMT2AMAPTMEN1RAB9AALDH1A1
	SCHEMBL16599389	0.88	TSHR (0.50)	SMN1; SMN2CYP1A2CYP2C9CYP2C19KMT2A
	SCHEMBL1313112	0.83	LOXL2 (0.51)	SMN1; SMN2LMNAKMT2AMAPTMEN1
	SCHEMBL11298531	0.82	SMN1; SMN2 (0.61)	SMN1; SMN2LMNAKMT2AMAPTMEN1
	SCHEMBL12909500	0.80	LMNA (0.44)	SMN1; SMN2LMNAKMT2AMAPTMEN1
	SCHEMBL16610053	0.80	MAPT (0.60)	SMN1; SMN2LMNACYP1A2CYP2C9CYP2C19
	SCHEMBL14016992	0.80	SMN1; SMN2 (0.58)	SMN1; SMN2LMNACYP1A2CYP2C9CYP2C19
	SCHEMBL18613360	0.79	KMT2A (0.49)	SMN1; SMN2LMNAKMT2AMAPTMEN1
	SCHEMBL28711315	0.79	ELANE (0.41)	KMT2APRSS1MEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.