Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | BCL9 | O00512 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18613361 | 0.94 | KMT2A (0.44) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL12909500 | 0.86 | LMNA (0.44) | KMT2AALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL28711315 | 0.85 | ELANE (0.41) | KMT2AELANENR4A2RXRARXRB | |
| SCHEMBL26264881 | 0.85 | AR (0.39) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL4590354 | 0.83 | KMT2A (0.44) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL14870985 | 0.82 | ELANE (0.47) | ELANEDRD2BACE1 | |
| SCHEMBL16610043 | 0.80 | MAPT (0.55) | KMT2AALDH1A1MAPTELANEMEN1 | |
| SCHEMBL32673207 | 0.80 | BACE1 (0.40) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL30498581 | 0.80 | ALDH1A1 (0.52) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL16610054 | 0.79 | SMN1; SMN2 (0.51) | KMT2AALDH1A1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063537-A | Prodrugs of directed lymphatics | 莫纳什大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-108137482-B | Prodrugs of directed lymphatics | 莫纳什大学 | 2024-03-15 | — | — | CN | disclosed |
| US-20240050573-A1 | LYMPH DIRECTING PRODRUGS | MONASH UNIVERSITY (AU) | 2024-02-15 | — | — | US | disclosed |
| US-11738087-B2 | Lymph directing prodrugs | MONASH UNIVERSITY (AU) | 2023-08-29 | — | — | US | disclosed |
| CN-114031658-A | Lymphatic prodrugs | 莫纳什大学 | 2022-02-11 | — | — | CN | disclosed |
| US-20180243425-A1 | LYMPH DIRECTING PRODRUGS | MONASH UNIVERSITY (AU) | 2018-08-30 | — | — | US | disclosed |
| EP-3347340-A1 | LYMPH DIRECTING PRODRUGS | Monash University (AU) | 2018-07-18 | — | — | EP | disclosed |
| WO-2017041139-A1 | LYMPH DIRECTING PRODRUGS | MONASH UNIVERSITY (AU) | 2017-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240050573-A1 | LYMPH DIRECTING PRODRUGS | LTA, ABCB11, LYN | KMT2A 4086/4885ALDH1A1 1056/4885LMNA 3766/4885 |
| US-20180243425-A1 | LYMPH DIRECTING PRODRUGS | MLNR, ABCB11, MLN | KMT2A 3956/4885ALDH1A1 1385/4885LMNA 3302/4885 |
| US-11738087-B2 | Lymph directing prodrugs | MLNR, ABCB11, MLN | KMT2A 3956/4885ALDH1A1 1385/4885LMNA 3302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.