Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1661170 | 0.80 | S1PR1 (0.53) | S1PR1 | |
| SCHEMBL1661572 | 0.74 | S1PR1 (0.41) | S1PR1 | |
| SCHEMBL1661650 | 0.71 | S1PR1 (0.42) | S1PR1 | |
| SCHEMBL1661564 | 0.68 | S1PR1 (0.50) | S1PR1 | |
| SCHEMBL1662093 | 0.66 | S1PR1 (0.43) | S1PR1 | |
| SCHEMBL29504589 | 0.63 | ALDH1A1 (0.35) | ALDH1A1HSD17B10 | |
| SCHEMBL15688609 | 0.63 | DYRK1A (0.44) | ALDH1A1HSD17B10 | |
| SCHEMBL2178656 | 0.63 | ALDH1A1 (0.35) | ALDH1A1HSD17B10 | |
| SCHEMBL1884419 | 0.63 | CYP1A2 (0.38) | ALDH1A1HSD17B10 | |
| SCHEMBL6152348 | 0.61 | OPRM1 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2306994-A1 | S1P1 RECEPTOR AGONISTS AND USE THEREOF | Amgen, Inc (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009154775-A1 | S1P1 RECEPTOR AGONISTS AND USE THEREOF | AMGEN INC. (US) | 2009-12-23 | — | — | WO | disclosed |