Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | GABRE | P78334 | 1/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1015260 | 0.87 | HSD11B1 (0.50) | HSD11B1SMN1; SMN2L3MBTL1GABRPGABRD | |
| SCHEMBL16803690 | 0.86 | GAA (0.42) | HSD11B1SMN1; SMN2L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL16612336 | 0.81 | ALDH1A1 (0.44) | SMN1; SMN2L3MBTL1ALDH1A1CYP2C9TP53 | |
| SCHEMBL23094635 | 0.80 | KDM6B (0.42) | L3MBTL1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL21385773 | 0.77 | HCAR2 (0.39) | L3MBTL1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL22473882 | 0.74 | HCAR2 (0.36) | L3MBTL1ALDH1A1CYP2C9KDM6BKDM4A | |
| SCHEMBL20964712 | 0.73 | KDM4E (0.39) | SMN1; SMN2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8328355 | 0.73 | GABRP (0.43) | SMN1; SMN2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL4773044 | 0.72 | ALDH1A1 (0.67) | SMN1; SMN2L3MBTL1ALDH1A1CYP2C9TP53 | |
| SCHEMBL13667410 | 0.72 | HSD11B1 (0.49) | HSD11B1ALDH1A1HPGDHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857397-B1 | FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2020-04-08 | — | — | EP | disclosed |
| US-9364000-B2 | Method of controlling pests with fused heterocyclic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-06-14 | — | — | US | disclosed |
| US-9364000-B2 | Method of controlling pests with fused heterocyclic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-06-14 | — | — | US | disclosed |
| US-9364000-B2 | Method of controlling pests with fused heterocyclic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-06-14 | — | — | US | disclosed |
| US-20150373982-A1 | METHOD OF CONTROLLING PESTS WITH FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2015-12-31 | — | — | US | disclosed |
| US-20150373982-A1 | METHOD OF CONTROLLING PESTS WITH FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2015-12-31 | — | — | US | disclosed |
| US-20150373982-A1 | METHOD OF CONTROLLING PESTS WITH FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2015-12-31 | — | — | US | disclosed |
| US-20150166573-A1 | FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-06-18 | — | — | US | disclosed |
| US-20150166573-A1 | FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-06-18 | — | — | US | disclosed |
| US-20150166573-A1 | FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-06-18 | — | — | US | disclosed |
| EP-2857397-A1 | FUSED HETEROCYCLIC COMPOUND | Sumitomo Chemical Company Limited (JP) | 2015-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150373982-A1 | METHOD OF CONTROLLING PESTS WITH FUSED HETEROCYCLIC COMPOUND | NR4A1, NR2E1, NR0B1 | HSD11B1 1661/4885SMN1; SMN2 1271/4885L3MBTL1 35/4885 |
| US-20150166573-A1 | FUSED HETEROCYCLIC COMPOUND | NR4A1, NR2E1, NR0B2 | HSD11B1 1782/4885SMN1; SMN2 1603/4885L3MBTL1 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.