Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16612776 | 0.84 | MAPT (0.55) | MEN1KMT2APKMALDH1A1L3MBTL1 | |
| SCHEMBL16612830 | 0.83 | MEN1 (0.47) | MEN1KMT2APKMALDH1A1L3MBTL1 | |
| SCHEMBL12479353 | 0.83 | MEN1 (0.64) | MEN1KMT2APKMALDH1A1MAPT | |
| SCHEMBL20420208 | 0.81 | TBXAS1 (0.46) | PKMALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL12497632 | 0.77 | HDAC2 (0.50) | MEN1KMT2APKMALDH1A1L3MBTL1 | |
| SCHEMBL16613040 | 0.77 | HCRTR1 (0.45) | MEN1KMT2APKMALDH1A1L3MBTL1 | |
| SCHEMBL21932615 | 0.76 | HDAC2 (0.49) | MEN1KMT2APKMALDH1A1L3MBTL1 | |
| SCHEMBL12479912 | 0.76 | HCRTR1 (0.45) | MEN1KMT2APKMALDH1A1L3MBTL1 | |
| SCHEMBL21932616 | 0.75 | HDAC2 (0.48) | MEN1KMT2APKMALDH1A1L3MBTL1 | |
| SCHEMBL12479169 | 0.75 | ALDH1A1 (0.47) | MEN1KMT2APKMALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675801-B1 | NOVEL PYRAZOLE AND IMIDAZOLE DERIVATIVES USEFUL AS OREXIN ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2015-04-08 | — | — | EP | disclosed |