SCHEMBL16613627

SCHEMBL16613627

Clc1nc(-c2ccc(-c3ccccc3)cc2)c2ccoc2n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.49
ALDH1A1 P00352 5/20 0.49
LMNA P02545 3/20 0.49
HPGD P15428 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
GLA P06280 1/20 0.49
MAPT P10636 3/20 0.45
KMT2A Q03164 5/20 0.40
OPRK1 P41145 1/20 0.40
L3MBTL1 Q9Y468 3/20 0.39
GAA P10253 2/20 0.39
MEN1 O00255 4/20 0.38
PKM P14618 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP1A2 P05177 1/20 0.35
PIK3R1 P27986 1/20 0.35
PIK3CA P42336 1/20 0.35
ADORA2A P29274 2/20 0.35
ADORA1 P30542 1/20 0.35
NUDT1 P36639 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16613689 0.97 KDM4E (0.52) KDM4EALDH1A1LMNAHPGDSMN1; SMN2
SCHEMBL17464092 0.89 ALDH1A1 (0.42) KDM4EALDH1A1LMNAHPGDSMN1; SMN2
SCHEMBL16613466 0.75 BCHE (0.38) KDM4EALDH1A1HPGDSMN1; SMN2MAPT
SCHEMBL17464087 0.74 KDM4E (0.50) KDM4EALDH1A1LMNAHPGDSMN1; SMN2
SCHEMBL808191 0.74 KDM4E (0.77) KDM4EALDH1A1LMNAHPGDSMN1; SMN2
SCHEMBL17286874 0.74 KDM4E (0.77) KDM4EALDH1A1LMNAHPGDSMN1; SMN2
SCHEMBL17367223 0.71 KDM4E (0.71) KDM4EALDH1A1LMNAHPGDSMN1; SMN2
SCHEMBL19639039 0.71 KDM4E (0.71) KDM4EALDH1A1LMNAHPGDSMN1; SMN2
SCHEMBL29992999 0.71 KDM4E (0.71) KDM4EALDH1A1LMNAHPGDSMN1; SMN2
SCHEMBL4439756 0.71 KDM4E (0.34) KDM4EALDH1A1LMNAHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230157160-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING THE SAME, AND ELECTRONIC DEVICE DUK SAN NEOLUX CO., LTD. (KR) 2023-05-18 US disclosed
US-20230157160-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING THE SAME, AND ELECTRONIC DEVICE DUK SAN NEOLUX CO., LTD. (KR) 2023-05-18 US disclosed
US-11552253-B2 Compound for organic electric device, organic electric device using same, and electronic device DUK SAN NEOLUX CO., LTD. (KR) 2023-01-10 US disclosed
US-11024805-B2 Compound for organic electric element, organic electric element using same, and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2021-06-01 US disclosed
US-20190097138-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2019-03-28 US disclosed
US-9917257-B2 Organic electronic element and an electronic device comprising it DUK SAN NEOLUX CO., LTD. (KR) 2018-03-13 US disclosed
US-9917257-B2 Organic electronic element and an electronic device comprising it DUK SAN NEOLUX CO., LTD. (KR) 2018-03-13 US disclosed
WO-2017171397-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2017-10-05 WO disclosed
WO-2017095075-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING SAME, AND ELECTRONIC DEVICE 덕산네오룩스 주식회사 2017-06-08 WO disclosed
US-20160028020-A1 ORGANIC ELECTRONIC ELEMENT AND AN ELECTRONIC DEVICE COMPRISING IT DUK SAN NEOLUX CO., LTD. (KR) 2016-01-28 US disclosed
US-20160028020-A1 ORGANIC ELECTRONIC ELEMENT AND AN ELECTRONIC DEVICE COMPRISING IT DUK SAN NEOLUX CO., LTD. (KR) 2016-01-28 US disclosed
WO-2015047058-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-04-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11024805-B2 Compound for organic electric element, organic electric element using same, and electronic device thereof PIEZO1, ORAI2, PER2 KDM4E 1316/4885ALDH1A1 2760/4885LMNA 2196/4885
US-20190097138-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF PIEZO1, ORAI2, PER2 KDM4E 1316/4885ALDH1A1 2760/4885LMNA 2196/4885
US-11552253-B2 Compound for organic electric device, organic electric device using same, and electronic device OR10J3, OR51E2, ORAI2 KDM4E 672/4885ALDH1A1 999/4885LMNA 2713/4885
US-20230157160-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING THE SAME, AND ELECTRONIC DEVICE OR10J3, OR51E2, ORAI2 KDM4E 671/4885ALDH1A1 1082/4885LMNA 2473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.