SCHEMBL16614441

SCHEMBL16614441

NN(c1ccc(-c2ncccn2)cc1)c1ccc(-c2ncncn2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 2/20 0.44
CLK4 Q9HAZ1 3/20 0.40
CYP2A6 P11509 1/20 0.38
AOC3 Q16853 2/20 0.33
PIK3CD O00329 1/20 0.33
PIP5K1C O60331 1/20 0.33
PI4KA P42356 1/20 0.33
PIK3CG P48736 1/20 0.33
PI4KB Q9UBF8 1/20 0.33
MAPT P10636 3/20 0.31
SMN1; SMN2 Q16637 3/20 0.31
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.31
TP53 P04637 2/20 0.31
HPGD P15428 2/20 0.31
HSD17B10 Q99714 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16614446 0.92 MEN1 (0.34) ADRB2MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL16614445 0.90 ADRB2 (0.52) ADRB2CLK4CYP2A6AOC3PIK3CD
SCHEMBL16614438 0.87 MAPT (0.46) CLK4MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL16614448 0.85 MAPT (0.47) ADRB2CLK4CYP2A6MAPTSMN1; SMN2
SCHEMBL21019111 0.81 CLK4 (0.44) ADRB2CLK4CYP2A6MAPTSMN1; SMN2
SCHEMBL21012485 0.80 ALDH1A1 (0.39) ADRB2CLK4CYP2A6PIK3CDMAPT
SCHEMBL16614443 0.79 NPC1 (0.45) ADRB2CLK4CYP2A6SMN1; SMN2NPC1
SCHEMBL16614435 0.77 CLK4 (0.41) ADRB2CLK4CYP2A6MAPTSMN1; SMN2
SCHEMBL18327352 0.75 CLK4 (0.44) ADRB2CLK4CYP2A6AOC3PIK3CD
SCHEMBL1421973 0.74 NPC1 (0.40) ADRB2CLK4CYP2A6PIK3CDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015046982-A2 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 2015-04-02 WO disclosed