SCHEMBL16614445

SCHEMBL16614445

NN(c1ccc(-c2ncccn2)cc1)c1ccc(-c2ncccn2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.52
CLK4 Q9HAZ1 3/20 0.47
CYP2A6 P11509 1/20 0.40
PIK3CD O00329 1/20 0.37
PIP5K1C O60331 1/20 0.37
PI4KA P42356 1/20 0.37
PIK3CG P48736 1/20 0.37
PI4KB Q9UBF8 1/20 0.37
AOC3 Q16853 2/20 0.37
NPC1 O15118 4/20 0.35
RAB9A P51151 4/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35
TP53 P04637 2/20 0.35
MAPT P10636 2/20 0.35
HPGD P15428 2/20 0.35
HSD17B10 Q99714 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16614441 0.90 ADRB2 (0.44) ADRB2CLK4CYP2A6PIK3CDPIP5K1C
SCHEMBL16614448 0.90 MAPT (0.47) ADRB2CLK4CYP2A6NPC1RAB9A
SCHEMBL16614443 0.87 NPC1 (0.45) ADRB2CLK4CYP2A6NPC1RAB9A
SCHEMBL16614446 0.80 MEN1 (0.34) ADRB2NPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL6685962 0.80 CLK4 (0.64) ADRB2CLK4CYP2A6PIK3CDPIP5K1C
SCHEMBL21019041 0.77 CLK4 (0.52) ADRB2CLK4CYP2A6SMN1; SMN2KDM4E
SCHEMBL61346 0.77 MAPT (0.56) ADRB2CLK4SMN1; SMN2KDM4EALDH1A1
SCHEMBL16625771 0.77 CLK4 (0.61) ADRB2CLK4CYP2A6PIK3CDPIP5K1C
SCHEMBL16614437 0.77 KDM4E (0.50) CYP2A6PIK3CDPI4KAPIK3CGPI4KB
SCHEMBL16614438 0.77 MAPT (0.46) CLK4NPC1RAB9ASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015046982-A2 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 2015-04-02 WO disclosed