Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 8/20 | 0.40 |
| ▸ | CDK8 | P49336 | 8/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
| ▸ | CBLB | Q13191 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16615358 | 0.91 | CCNC (0.46) | CCNCCDK8 | |
| SCHEMBL16615215 | 0.85 | ALK (0.50) | KDM4EPOLBHTTEPHX2RAB9A | |
| SCHEMBL16615074 | 0.83 | MAPT (0.45) | KDM4EPOLBHTTEPHX2RAB9A | |
| SCHEMBL16615299 | 0.83 | POLB (0.41) | POLBEPHX2CCNCCDK8RAB9A | |
| SCHEMBL16615217 | 0.83 | KCNQ2 (0.44) | KDM4EPOLBHTTRAB9A | |
| SCHEMBL16615216 | 0.81 | ALK (0.49) | CCNCCDK8 | |
| SCHEMBL16615102 | 0.77 | MAPT (0.44) | KDM4EPOLBHTTRAB9A | |
| SCHEMBL17918786 | 0.73 | ALK (0.46) | KDM4EPOLBHTTEPHX2RAB9A | |
| SCHEMBL17918724 | 0.71 | CCNC (0.47) | CCNCCDK8 | |
| SCHEMBL16615305 | 0.71 | KMT2A (0.40) | KDM4EPOLBHTTRAB9AGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015047133-A1 | NOVEL CHEMICAL COMPOUNDS (VARIANTS) AND THE USE THEREOF TO TREAT ONCOLOGICAL DISEASES | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "ОТЕЧЕСТВЕННЫЕ ФАРМАЦЕВТИЧЕСКИЕ ТЕХНОЛОГИИ" | 2015-04-02 | — | — | WO | disclosed |