Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 12/20 | 0.46 |
| ▸ | CDK8 | P49336 | 12/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | MC5R | P33032 | 1/20 | 0.40 |
| ▸ | MC3R | P41968 | 1/20 | 0.40 |
| ▸ | MC1R | Q01726 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16615299 | 0.92 | POLB (0.41) | CCNCCDK8MC5RMAPTFLT3 | |
| SCHEMBL16615074 | 0.92 | MAPT (0.45) | MAPTFLT3 | |
| SCHEMBL16615268 | 0.91 | KDM4E (0.41) | CCNCCDK8 | |
| SCHEMBL16615216 | 0.90 | ALK (0.49) | CCNCCDK8MC4RMC5RMC3R | |
| SCHEMBL16615102 | 0.82 | MAPT (0.44) | MAPT | |
| SCHEMBL17918724 | 0.79 | CCNC (0.47) | CCNCCDK8MAPTFLT3ALK | |
| SCHEMBL16615217 | 0.78 | KCNQ2 (0.44) | MAPT | |
| SCHEMBL16615213 | 0.76 | EPHX2 (0.43) | MAPTFLT3 | |
| SCHEMBL16615215 | 0.76 | ALK (0.50) | ALK | |
| SCHEMBL20859294 | 0.75 | CCNC (0.41) | CCNCCDK8MC4RMC5RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015047133-A1 | NOVEL CHEMICAL COMPOUNDS (VARIANTS) AND THE USE THEREOF TO TREAT ONCOLOGICAL DISEASES | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "ОТЕЧЕСТВЕННЫЕ ФАРМАЦЕВТИЧЕСКИЕ ТЕХНОЛОГИИ" | 2015-04-02 | — | — | WO | disclosed |