Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.39 |
| ▸ | MAP3K1 | Q13233 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.39 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | MC5R | P33032 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16615358 | 0.92 | CCNC (0.46) | MC5RFLT3MAPTALKCFTR | |
| SCHEMBL16615074 | 0.90 | MAPT (0.45) | POLBHPGDKMT2ALMNAEPHX2 | |
| SCHEMBL16615268 | 0.83 | KDM4E (0.41) | POLBTP53EPHX2RAB9ACCNC | |
| SCHEMBL16615216 | 0.82 | ALK (0.49) | MC5RALKCCNCCDK8 | |
| SCHEMBL16615102 | 0.81 | MAPT (0.44) | POLBHPGDKMT2ALMNARAB9A | |
| SCHEMBL16615113 | 0.80 | ALK (0.47) | POLBUSP2HPGDMETMAP4K2 | |
| SCHEMBL16615217 | 0.77 | KCNQ2 (0.44) | POLBUSP2HPGDKMT2AALOX15 | |
| SCHEMBL20859358 | 0.76 | POLB (0.39) | POLBUSP2HPGDMETMAP4K2 | |
| SCHEMBL16615213 | 0.75 | EPHX2 (0.43) | HPGDKMT2ALMNAEPHX2FLT3 | |
| SCHEMBL16615215 | 0.74 | ALK (0.50) | POLBHPGDKMT2ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015047133-A1 | NOVEL CHEMICAL COMPOUNDS (VARIANTS) AND THE USE THEREOF TO TREAT ONCOLOGICAL DISEASES | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "ОТЕЧЕСТВЕННЫЕ ФАРМАЦЕВТИЧЕСКИЕ ТЕХНОЛОГИИ" | 2015-04-02 | — | — | WO | disclosed |