SCHEMBL16615529

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL83335	0.89	MMP3 (0.57)	ESR1ESR2MMP3PDE3BPDE3A
	SCHEMBL15834317	0.86	MMP3 (0.63)	ESR1ESR2MMP3PDE3BPDE3A
	SCHEMBL16582522	0.82	ESR1 (0.50)	ESR1ESR2MMP3CA12CA2
	SCHEMBL28165919	0.82	MMP3 (0.57)	ESR1ESR2MMP3PDE3BPDE3A
	SCHEMBL397141	0.80	KIF11 (0.61)	MMP3PDE3BPDE3ACA12CA2
	SCHEMBL19579048	0.78	KIF11 (0.52)	MMP3PDE3BPDE3ACA12CA2
	SCHEMBL6068004	0.77	MMP3 (0.63)	ESR2MMP3CA12CA2CA3
	SCHEMBL27806612	0.77	KIF11 (0.51)	MMP3PDE3BPDE3ACA12CA2
	SCHEMBL19579265	0.76	KIF11 (0.50)	MMP3PDE3BPDE3ACA12CA2
	SCHEMBL2649287	0.76	KIF11 (0.44)	MMP3PDE3BPDE3ACA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.