Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.59 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.58 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16615796 | 0.86 | GFER (0.56) | HDAC1HDAC6RAB9ACA12CA1 | |
| SCHEMBL1003735 | 0.84 | TP53 (0.68) | HDAC1HDAC6GAAMAPTALDH1A1 | |
| SCHEMBL16615800 | 0.82 | RORC (0.66) | HDAC1HDAC6RAB9AHDAC3HDAC2 | |
| SCHEMBL16615807 | 0.80 | NPC1 (0.63) | RAB9ASMN1; SMN2NPC1GAAMEN1 | |
| SCHEMBL9694832 | 0.79 | MLYCD (0.72) | HDAC1HDAC6SMN1; SMN2NPC1GAA | |
| SCHEMBL18103163 | 0.79 | NPC1 (0.88) | HDAC6RAB9AHDAC2CACNA1BAPBA1 | |
| SCHEMBL14715824 | 0.79 | NPC1 (0.88) | HDAC6RAB9AHDAC2CACNA1BAPBA1 | |
| SCHEMBL9877204 | 0.78 | CACNA1B (0.65) | RAB9ACACNA1BAPBA1SMN1; SMN2NPC1 | |
| SCHEMBL27611454 | 0.78 | RORC (0.65) | HDAC1HDAC6RAB9AHDAC3HDAC2 | |
| SCHEMBL4167802 | 0.78 | TP53 (0.59) | HDAC1HDAC6GAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015042685-A1 | INHIBITORS OF POLYNUCLEOTIDE REPEAT-ASSOCIATED RNA FOCI AND USES THEREOF | VALORISATION-RECHERCHE (CA) | 2015-04-02 | — | — | WO | disclosed |