Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.68 |
| ▸ | PKM | P14618 | 3/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16206624 | 0.80 | ALDH1A1 (0.79) | ALDH1A1PKMNPSR1MAPTHPGD | |
| SCHEMBL1723104 | 0.79 | NPC1 (0.76) | ALDH1A1PKMHPGDLMNAGAA | |
| SCHEMBL2703492 | 0.79 | ALDH1A1 (0.74) | ALDH1A1PKMNPSR1MAPTLMNA | |
| SCHEMBL8266867 | 0.78 | MEN1 (0.66) | ALDH1A1PKMHPGDLMNAMEN1 | |
| SCHEMBL28023852 | 0.78 | ALDH1A1 (0.82) | ALDH1A1PKMNPSR1MAPTLMNA | |
| SCHEMBL30390171 | 0.78 | ALDH1A1 (0.58) | ALDH1A1PKMNPSR1MAPTHPGD | |
| SCHEMBL29031229 | 0.78 | MEN1 (0.77) | ALDH1A1PKMNPSR1MAPTHPGD | |
| SCHEMBL17947766 | 0.77 | ALDH1A1 (1.00) | ALDH1A1PKMNPSR1MAPTHPGD | |
| SCHEMBL9864972 | 0.76 | NPC1 (0.67) | ALDH1A1PKMMAPTHPGDLMNA | |
| SCHEMBL15010186 | 0.75 | ALDH1A1 (0.73) | ALDH1A1PKMHPGDLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015042685-A1 | INHIBITORS OF POLYNUCLEOTIDE REPEAT-ASSOCIATED RNA FOCI AND USES THEREOF | VALORISATION-RECHERCHE (CA) | 2015-04-02 | — | — | WO | disclosed |