Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PKLR | P30613 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30389993 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KDM4EPKMMAPTKMT2A | |
| SCHEMBL30389759 | 0.81 | PKM (0.57) | ALDH1A1KDM4EPKMGAAPKLR | |
| SCHEMBL30880106 | 0.80 | PKLR (0.62) | ALDH1A1PKMGAATSHRPKLR | |
| SCHEMBL30390158 | 0.80 | ALDH1A1 (0.59) | ALDH1A1KDM4EPKMGAAPKLR | |
| SCHEMBL2702270 | 0.79 | PKLR (0.75) | PKMPKLR | |
| SCHEMBL30388775 | 0.79 | PKLR (0.75) | PKMPKLR | |
| SCHEMBL18754084 | 0.79 | KDM4E (0.57) | ALDH1A1KDM4ENAMPTHIF1AEPAS1 | |
| SCHEMBL30390083 | 0.79 | PKM (0.57) | ALDH1A1KDM4EPKMGAAPKLR | |
| SCHEMBL16615805 | 0.78 | ALDH1A1 (0.68) | ALDH1A1KDM4EPKMNPSR1MAPT | |
| SCHEMBL94316 | 0.75 | KDM4E (0.61) | ALDH1A1KDM4EKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115957219-A | Application of depolymerizing agent of M2 subtype pyruvate kinase aggregate in preparation of anti-aging drugs | 北京大学 | 2023-04-14 | — | — | CN | disclosed |