Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CTRC | Q99895 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1660011 | 0.86 | RAD51 (0.51) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL1658724 | 0.85 | RAB9A (0.47) | KDM5BALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL8100226 | 0.83 | KDM4E (0.59) | KDM5BALDH1A1MAPTPSDNPC1 | |
| SCHEMBL1660676 | 0.80 | KDM4E (0.45) | KDM5BALDH1A1MAPTPSDKDM4E | |
| SCHEMBL8105987 | 0.79 | NPC1 (0.55) | KDM5BALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL1660002 | 0.77 | ENPP2 (0.42) | KDM5BALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL1659969 | 0.77 | NPC1 (0.47) | KDM5BALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL21902776 | 0.74 | IDH1 (0.46) | MAPTNPC1KDM4E | |
| SCHEMBL11919885 | 0.72 | KDM4E (0.70) | ALDH1A1MAPTPSDNPC1RAB9A | |
| SCHEMBL8100199 | 0.72 | KDM4E (0.64) | ALDH1A1MAPTNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2314588-B1 | 4H-Pyrido[1,2-a]pyrimidin-4-one derivatives as modulators of the estrogen-related receptors | GUANGZHOU INST BIOMED & HEALTH (CN) | 2014-11-05 | — | — | EP | claimed |
| EP-3327017-B1 | BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | MERCK PATENT GMBH (DE) | 2019-04-24 | — | — | EP | disclosed |
| US-10183935-B2 | Benzamide derivatives as modulators of the follicle stimulating hormone | MERCK PATENT GMBH (DE) | 2019-01-22 | — | — | US | disclosed |
| EP-3327017-A1 | BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Merck Patent GmbH (DE) | 2018-05-30 | — | — | EP | disclosed |
| US-20170226096-A1 | BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | MERCK PATENT GMBH (DE) | 2017-08-10 | — | — | US | disclosed |
| US-9409897-B2 | Benzamide derivatives as modulators of the follicle stimulating hormone | MERCK PATENT GMBH (DE) | 2016-08-09 | — | — | US | disclosed |
| US-20160137632-A1 | BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | MERCK PATENT GMBH (DE) | 2016-05-19 | — | — | US | disclosed |
| US-20150011544-A1 | COMPOUNDS OF ESTROGEN-RELATED RECEPTOR MODULATORS AND THE USES THEREOF | GUANGZHOU INST OF BIOMEDICINE & HEALTH CHINESE ACADEMY OF SCIENCES (CN) | 2015-01-08 | — | — | US | disclosed |
| US-20150011544-A1 | COMPOUNDS OF ESTROGEN-RELATED RECEPTOR MODULATORS AND THE USES THEREOF | GUANGZHOU INST OF BIOMEDICINE & HEALTH CHINESE ACADEMY OF SCIENCES (CN) | 2015-01-08 | — | — | US | disclosed |
| US-20150011544-A1 | COMPOUNDS OF ESTROGEN-RELATED RECEPTOR MODULATORS AND THE USES THEREOF | GUANGZHOU INST OF BIOMEDICINE & HEALTH CHINESE ACADEMY OF SCIENCES (CN) | 2015-01-08 | — | — | US | disclosed |
| US-8853221-B2 | Compounds of estrogen-related receptor modulators and the uses thereof | GUANGZHOU INSTITUTE OF BIOMEDICINE & HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2014-10-07 | — | — | US | disclosed |
| US-8853221-B2 | Compounds of estrogen-related receptor modulators and the uses thereof | GUANGZHOU INSTITUTE OF BIOMEDICINE & HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2014-10-07 | — | — | US | disclosed |
| US-8853221-B2 | Compounds of estrogen-related receptor modulators and the uses thereof | GUANGZHOU INSTITUTE OF BIOMEDICINE & HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2014-10-07 | — | — | US | disclosed |
| CN-101628913-B | Compounds useful as estrogen-related receptor modulators and uses thereof | GUANGZHOU INST BIOMED & HEALTH | 2013-01-23 | — | — | CN | disclosed |
| US-20110218196-A1 | COMPOUNDS OF ESTROGEN-RELATED RECEPTOR MODULATORS AND THE USES THEREOF | GUANGZHOU INSTITUTE OF BIOMEDICINE & HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2011-09-08 | — | — | US | disclosed |
| US-20110218196-A1 | COMPOUNDS OF ESTROGEN-RELATED RECEPTOR MODULATORS AND THE USES THEREOF | GUANGZHOU INSTITUTE OF BIOMEDICINE & HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2011-09-08 | — | — | US | disclosed |
| US-20110218196-A1 | COMPOUNDS OF ESTROGEN-RELATED RECEPTOR MODULATORS AND THE USES THEREOF | GUANGZHOU INSTITUTE OF BIOMEDICINE & HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2011-09-08 | — | — | US | disclosed |
| EP-2314588-A1 | COMPOUNDS OF ESTROGEN-RELATED RECEPTOR MODULATORS AND THE USES THEREOF | Guangzhou Institute Of Biomedicine And Health, Chinese Academy Of Sciences (CN) | 2011-04-27 | — | — | EP | disclosed |
| EP-2314588-A1 | COMPOUNDS OF ESTROGEN-RELATED RECEPTOR MODULATORS AND THE USES THEREOF | Guangzhou Institute Of Biomedicine And Health, Chinese Academy Of Sciences (CN) | 2011-04-27 | — | — | EP | disclosed |
| CN-101628913-A | Compounds useful as estrogen-related receptor modulators and uses thereof | GUANGZHOU INST BIOMED & HEALTH | 2010-01-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137632-A1 | BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | FSHR, GNRHR, SHBG | KDM5B 2574/4885ALDH1A1 3363/4885MAPT 4813/4885 |
| US-20170226096-A1 | BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | FSHR, GNRHR, SHBG | KDM5B 2574/4885ALDH1A1 3363/4885MAPT 4813/4885 |
| US-20110218196-A1 | COMPOUNDS OF ESTROGEN-RELATED RECEPTOR MODULATORS AND THE USES THEREOF | ESRRA, ESRRB, ESRRG | KDM5B 1564/4885ALDH1A1 594/4885MAPT 4326/4885 |
| US-20150011544-A1 | COMPOUNDS OF ESTROGEN-RELATED RECEPTOR MODULATORS AND THE USES THEREOF | ESRRA, ESRRB, ESRRG | KDM5B 1564/4885ALDH1A1 594/4885MAPT 4326/4885 |
| US-10183935-B2 | Benzamide derivatives as modulators of the follicle stimulating hormone | FSHR, GNRHR, SHBG | KDM5B 2574/4885ALDH1A1 3363/4885MAPT 4813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.