SCHEMBL1661638

SCHEMBL1661638

c1ccc(N(CC2CO2)CC2CO2)c(CCCCCCCCCc2ccccc2N(CC2CO2)CC2CO2)c1

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
LMNA P02545 2/20 0.36
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MGLL Q99685 2/20 0.32
USP2 O75604 1/20 0.32
LIPG Q9Y5X9 1/20 0.31
ALDH1A1 P00352 2/20 0.31
POLB P06746 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10413043 0.95 KDM4E (0.37) KDM4ELMNAMEN1KMT2ATDP1
SCHEMBL6865362 0.85 KDM4E (0.35) KDM4ELMNATDP1USP2ALDH1A1
SCHEMBL29703193 0.84 KDM4E (0.38) KDM4ELMNAMEN1KMT2ATDP1
SCHEMBL625141 0.84 KDM4E (0.38) KDM4ELMNAMEN1KMT2ATDP1
SCHEMBL31544651 0.83 KDM4E (0.38) KDM4ELMNATDP1USP2ALDH1A1
SCHEMBL6436617 0.83 KDM4E (0.38) KDM4ELMNATDP1USP2ALDH1A1
SCHEMBL6230504 0.82 LMNA (0.43) KDM4ELMNAMEN1KMT2ATDP1
SCHEMBL30015922 0.82 LMNA (0.43) KDM4ELMNAMEN1KMT2ATDP1
SCHEMBL11115495 0.81 CTSB (0.42) KDM4ELMNAMEN1KMT2ATDP1
SCHEMBL21704540 0.79 TDP1 (0.39) KDM4ELMNAMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2898863-A1 Method and manufacture of a wound dressing for covering an open wound Covidien LP (US) 2015-07-29 EP disclosed
EP-1299059-B1 METHOD AND MANUFACTURE OF A WOUND DRESSING FOR COVERING AN OPEN WOUND COVIDIEN LP (US) 2015-02-18 EP disclosed
EP-2308430-A2 Method and manufacture of a wound dressing for covering an open wound Tyco Healthcare Group LP (US) 2011-04-13 EP disclosed
EP-1299059-A4 METHOD AND MANUFACTURE OF A WOUND DRESSING FOR COVERING AN OPEN WOUND TYCO HEALTHCARE (US) 2005-02-09 EP disclosed
EP-1299059-A1 METHOD AND MANUFACTURE OF A WOUND DRESSING FOR COVERING AN OPEN WOUND Tyco Healthcare Group LP (US) 2003-04-09 EP disclosed
US-6369289-B1 Method and manufacture of a wound dressing for covering an open wound TYCO HEALTHCARE GROUP LP 2002-04-09 US disclosed
WO-2002003899-A1 METHOD AND MANUFACTURE OF A WOUND DRESSING FOR COVERING AN OPEN WOUND TYCO HEALTHCARE GROUP LP (US) 2002-01-17 WO disclosed