SCHEMBL16616707

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL853782	0.91	HSD17B2 (0.49)	MAPTKMT2ASMN1; SMN2MEN1HSD17B2
	SCHEMBL15390848	0.89	CA12 (0.50)	MAPTSMN1; SMN2TSHRALDH1A1KDM4E
	SCHEMBL15305553	0.83	EPHX1 (0.44)	MAPTKMT2ASMN1; SMN2MEN1ALDH1A1
	SCHEMBL6122016	0.82	PYCR1 (0.43)	MAPTKMT2ASMN1; SMN2MEN1ALDH1A1
	SCHEMBL8251185	0.81	MAPT (0.54)	MAPTKMT2ASMN1; SMN2MEN1HSD17B2
	SCHEMBL20212292	0.81	ALDH1A1 (0.56)	MAPTKMT2ASMN1; SMN2MEN1HSD17B2
	SCHEMBL30036817	0.81	ALDH1A1 (0.56)	MAPTKMT2ASMN1; SMN2MEN1HSD17B2
	SCHEMBL8732462	0.80	MAPT (0.53)	MAPTKMT2ASMN1; SMN2MEN1HSD17B2
	SCHEMBL31295843	0.79	ACACB (0.39)	MAPTKMT2AMEN1ALDH1A1
	SCHEMBL27942554	0.79	MTNR1A (0.51)	KMT2AMEN1TSHRALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.