Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6120000 | 0.89 | ALDH1A1 (0.43) | PYCR1ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL15305553 | 0.84 | EPHX1 (0.44) | ALDH1A1MEN1KMT2ASMN1; SMN2LPAR1 | |
| SCHEMBL15305570 | 0.84 | PYCR1 (0.38) | PYCR1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL15390848 | 0.82 | CA12 (0.50) | ALDH1A1KDM4ESMN1; SMN2LMNAGAA | |
| SCHEMBL16616707 | 0.82 | MAPT (0.48) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24981985 | 0.82 | ALDH1A1 (0.47) | PYCR1ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL28989317 | 0.82 | ALDH1A1 (0.47) | PYCR1ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL31295843 | 0.80 | ACACB (0.39) | ALDH1A1MEN1KMT2AGAAUSP2 | |
| SCHEMBL27942554 | 0.80 | MTNR1A (0.51) | ALDH1A1MEN1KMT2AGAAHTT | |
| SCHEMBL30036398 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KDM4ETDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130267532-A1 | CYCLIC AMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF DISEASE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2013-10-10 | — | — | US | disclosed |
| US-20130267532-A1 | CYCLIC AMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF DISEASE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2013-10-10 | — | — | US | disclosed |
| EP-2640716-A1 | CYCLIC AMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF DISEASE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2013-09-25 | — | — | EP | disclosed |
| WO-2012067268-A1 | CYCLIC AMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF DISEASE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-05-24 | — | — | WO | disclosed |
| WO-2012067268-A1 | CYCLIC AMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF DISEASE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130267532-A1 | CYCLIC AMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF DISEASE | CCNI, CCNT1, CCNT2 | PYCR1 170/4885ALDH1A1 403/4885KDM4E 3301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.