Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17468940 | 0.90 | MAOA (0.52) | DHFRMAOBMAOAAOC3TSHR | |
| SCHEMBL30270552 | 0.89 | MAOB (0.53) | DHFRMAOBMAOAAOC3TSHR | |
| SCHEMBL17064852 | 0.89 | MAOB (0.53) | DHFRMAOBMAOAAOC3TSHR | |
| SCHEMBL29892730 | 0.81 | CRHBP (0.54) | MAOBMAOATSHRSMN1; SMN2CRHBP | |
| SCHEMBL7207372 | 0.81 | CRHBP (0.54) | MAOBMAOATSHRSMN1; SMN2CRHBP | |
| SCHEMBL642317 | 0.80 | CRHBP (0.61) | MAOBMAOAAOC3TSHRALDH1A1 | |
| SCHEMBL10693193 | 0.80 | SIGMAR1 (0.51) | DHFRAOC3TSHRALDH1A1CRHBP | |
| SCHEMBL9638314 | 0.80 | RAB9A (0.55) | DHFRAOC3TSHRALDH1A1CRHBP | |
| SCHEMBL24124892 | 0.79 | CRHBP (0.57) | DHFRMAOBMAOAAOC3TSHR | |
| SCHEMBL6606938 | 0.79 | NR1H2 (0.54) | DHFRMAOBMAOAAOC3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2828339-B1 | CARBOXYLATE DYES | MILLIKEN & CO (US) | 2018-10-31 | — | — | EP | disclosed |
| US-9187717-B2 | Carboxylate dyes | MILLIKEN & COMPANY (US) | 2015-11-17 | — | — | US | disclosed |
| US-20150099869-A1 | Carboxylate Dyes | MILLIKEN & COMPANY | 2015-04-09 | — | — | US | disclosed |
| CN-104350106-A | Laundry care compositions containing dyes | PROCTER & GAMBLE | 2015-02-11 | — | — | CN | disclosed |
| CN-104220535-A | Carboxylate dyes | MILLIKEN & CO | 2014-12-17 | — | — | CN | disclosed |