SCHEMBL16617642

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL26037653	0.84	CYP1A2 (0.64)	CYP1A2CYP3A4MAPTCYP2C19RAB9A
	SCHEMBL120471	0.84	MAOA (0.66)	CYP1A2CYP3A4MAPTCYP2C19RAB9A
	SCHEMBL27804745	0.81	F2 (0.64)	CYP1A2CYP3A4MAPTCYP2C19RAB9A
	SCHEMBL8817473	0.80	CYP1A2 (0.54)	CYP1A2CYP3A4MAPTCYP2C19RAB9A
	SCHEMBL27594531	0.79	TUBB4A (0.67)	CYP1A2CYP3A4MAPTCYP2C19RAB9A
	SCHEMBL23734343	0.78	F2 (0.60)	CYP1A2CYP3A4MAPTCYP2C19RAB9A
	SCHEMBL24786952	0.78	CYP1A2 (0.57)	CYP1A2CYP3A4MAPTCYP2C19RAB9A
	SCHEMBL105928	0.78	KDM4E (0.72)	CYP1A2CYP3A4MAPTCYP2C19RAB9A
	SCHEMBL6447473	0.78	F2 (0.59)	CYP1A2CYP3A4MAPTCYP2C19RAB9A
	SCHEMBL27664194	0.78	F2 (0.59)	CYP1A2CYP3A4MAPTCYP2C19RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.