Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CSF3R | Q99062 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16617207 | 0.91 | TLR8 (0.36) | TLR8TDP1TSHRTP53CYP3A4 | |
| SCHEMBL16618016 | 0.85 | ALOX15 (0.42) | TSHRTP53CYP3A4SYKKDM4E | |
| SCHEMBL10139683 | 0.81 | CYP3A4 (0.42) | TDP1TSHRTP53CYP3A4SYK | |
| SCHEMBL16618104 | 0.80 | TSHR (0.40) | TSHRTP53CYP3A4MAPTHTR7 | |
| SCHEMBL27991423 | 0.79 | CYP3A4 (0.40) | TLR8TDP1TSHRTP53CYP3A4 | |
| SCHEMBL16617357 | 0.75 | TSHR (0.42) | TSHRTP53CYP3A4KDM4EMAPT | |
| SCHEMBL16617470 | 0.75 | TSHR (0.41) | TLR8TSHRTP53CYP3A4MAPT | |
| SCHEMBL16617493 | 0.75 | CYP3A4 (0.47) | TDP1TSHRTP53CYP3A4SYK | |
| SCHEMBL16576516 | 0.75 | APP (0.38) | TDP1TSHRTP53CYP3A4SYK | |
| SCHEMBL16616912 | 0.74 | ALDH1A1 (0.37) | TSHRTP53CYP3A4KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2828339-B1 | CARBOXYLATE DYES | MILLIKEN & CO (US) | 2018-10-31 | — | — | EP | disclosed |
| US-9187717-B2 | Carboxylate dyes | MILLIKEN & COMPANY (US) | 2015-11-17 | — | — | US | disclosed |
| US-20150099869-A1 | Carboxylate Dyes | MILLIKEN & COMPANY | 2015-04-09 | — | — | US | disclosed |