Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.52 |
| ▸ | FNTA | P49354 | 3/20 | 0.49 |
| ▸ | FNTB | P49356 | 3/20 | 0.49 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.47 |
| ▸ | RRM1 | P23921 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19839845 | 0.84 | SIRT6 (0.63) | SIRT6SIRT1FNTAFNTBRRM1 | |
| SCHEMBL28420491 | 0.82 | CTSK (0.65) | SIRT6SIRT1FNTAFNTBALDH1A1 | |
| SCHEMBL4950657 | 0.80 | SIRT6 (0.51) | SIRT6SIRT1FNTAFNTBRRM1 | |
| SCHEMBL4948525 | 0.80 | SIRT6 (0.51) | SIRT6SIRT1FNTAFNTBRRM1 | |
| SCHEMBL4949210 | 0.80 | SIRT6 (0.51) | SIRT6SIRT1FNTAFNTBRRM1 | |
| SCHEMBL19839611 | 0.80 | SIRT1 (0.80) | SIRT6SIRT1FNTAFNTBRRM1 | |
| SCHEMBL19839612 | 0.80 | SIRT1 (0.80) | SIRT6SIRT1FNTAFNTBRRM1 | |
| SCHEMBL27150679 | 0.80 | SIRT6 (0.59) | SIRT6SIRT1FNTAFNTBRRM1 | |
| SCHEMBL18837464 | 0.79 | DPP7 (0.50) | SIRT6SIRT1FNTAFNTBRRM1 | |
| SCHEMBL18837473 | 0.79 | DPP7 (0.50) | SIRT6SIRT1FNTAFNTBRRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834393-B2 | Organic compounds having taste-modifying properties | GIVAUDAN SA (CH) | 2023-12-05 | — | — | US | disclosed |
| US-20210147345-A1 | Organic Compounds having Taste-Modifying Properties | GIVAUDAN SA (CH) | 2021-05-20 | — | — | US | disclosed |
| EP-3057444-B1 | ORGANIC COMPOUNDS HAVING TASTE-MODIFYING PROPERTIES | GIVAUDAN SA (CH) | 2017-12-06 | — | — | EP | disclosed |
| EP-3057444-A1 | ORGANIC COMPOUNDS HAVING TASTE-MODIFYING PROPERTIES | Givaudan SA (CH) | 2016-08-24 | — | — | EP | disclosed |
| US-20160227825-A1 | Organic Compounds having Taste-Modifying Properties | GIVAUDAN SA (CH) | 2016-08-11 | — | — | US | disclosed |
| WO-2015048991-A1 | ORGANIC COMPOUNDS HAVING TASTE-MODIFYING PROPERTIES | GIVAUDAN SA (CH) | 2015-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160227825-A1 | Organic Compounds having Taste-Modifying Properties | TAS2R5, TAS2R3, TAS2R1 | SIRT6 3267/4885SIRT1 3859/4885FNTA 2611/4885 |
| US-11834393-B2 | Organic compounds having taste-modifying properties | TAS2R5, TAS2R3, TAS2R1 | SIRT6 3267/4885SIRT1 3859/4885FNTA 2611/4885 |
| US-20210147345-A1 | Organic Compounds having Taste-Modifying Properties | TAS2R5, TAS2R3, TAS2R1 | SIRT6 3267/4885SIRT1 3859/4885FNTA 2611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.