SCHEMBL16618589

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16618630	0.90	HTR6 (0.45)	HTR6PDE4APDE4BPDE4CPDE4D
	SCHEMBL16618625	0.90	PDE4A (0.40)	HTR6PDE4APDE4BPDE4CPDE4D
	SCHEMBL16626620	0.89	SLC6A2 (0.43)	HTR6PDE4APDE4BPDE4CPDE4D
	SCHEMBL16619084	0.84	HTR6 (0.46)	HTR6PDE4APDE4BPDE4CPDE4D
	SCHEMBL16626519	0.84	HTR6 (0.43)	HTR6PDE4APDE4BPDE4CPDE4D
	Hydrochloric Acid SCHEMBL16619581	0.83	HTR6 (0.42)	HTR6PDE4APDE4BPDE4CPDE4D
	SCHEMBL16618846	0.83	HTR6 (0.43)	HTR6PDE4APDE4BPDE4CPDE4D
	SCHEMBL16619014	0.82	HTR6 (0.37)	HTR6PDE4APDE4BPDE4CPDE4D
	SCHEMBL16619072	0.82	RORC (0.41)	HTR6PDE4APDE4BPDE4CPDE4D
	SCHEMBL16626636	0.82	PDE4A (0.42)	HTR6PDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.