Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 13/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 12/20 | 0.47 |
| ▸ | BRD4 | O60885 | 14/20 | 0.46 |
| ▸ | BRD2 | P25440 | 9/20 | 0.45 |
| ▸ | BRD3 | Q15059 | 9/20 | 0.45 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | BRD1 | O95696 | 1/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CCL2 | P13500 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | TAF1 | P21675 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16618930 | 0.91 | BRD4 (0.44) | CYP3A4CYP2C9BRD4BRD2BRD3 | |
| SCHEMBL11909203 | 0.90 | BRD4 (0.55) | CYP3A4CYP2C9BRD4BRD2BRD3 | |
| SCHEMBL16619338 | 0.90 | BRD4 (0.55) | CYP3A4CYP2C9BRD4BRD2BRD3 | |
| SCHEMBL16619406 | 0.82 | BRD4 (0.44) | CYP3A4CYP2C9BRD4BRD2BRD3 | |
| SCHEMBL16619386 | 0.82 | BRD4 (0.43) | CYP3A4CYP2C9BRD4BRD2BRD3 | |
| SCHEMBL16619324 | 0.80 | CYP3A4 (0.48) | CYP3A4CYP2C9BRD4BRD2BRD3 | |
| SCHEMBL1907697 | 0.80 | BRD4 (0.57) | CYP3A4CYP2C9BRD4BRD2BRD3 | |
| SCHEMBL16619529 | 0.79 | LMNA (0.55) | CYP3A4CYP2C9BRD4BRD2BRD3 | |
| SCHEMBL16619532 | 0.79 | LMNA (0.55) | CYP3A4CYP2C9BRD4BRD2BRD3 | |
| SCHEMBL17967387 | 0.79 | BRD4 (0.49) | CYP3A4CYP2C9BRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |