Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | BRD4 | O60885 | 6/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | BRD2 | P25440 | 3/20 | 0.52 |
| ▸ | BRD3 | Q15059 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16619529 | 1.00 | LMNA (0.55) | LMNABRD4CYP3A4CYP2C9BRD2 | |
| SCHEMBL16619284 | 0.86 | LMNA (0.59) | LMNABRD4CYP3A4CYP2C9BRD2 | |
| SCHEMBL16619289 | 0.86 | LMNA (0.59) | LMNABRD4CYP3A4CYP2C9BRD2 | |
| SCHEMBL11909203 | 0.84 | BRD4 (0.55) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL16619338 | 0.84 | BRD4 (0.55) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL1908339 | 0.82 | BRD4 (0.71) | LMNABRD4CYP3A4CYP2C9BRD2 | |
| SCHEMBL16618802 | 0.79 | CYP3A4 (0.47) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL10589261 | 0.78 | GALR3 (0.49) | POLBTP53ALDH1A1GAAHTT | |
| SCHEMBL16618930 | 0.77 | BRD4 (0.44) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL1908122 | 0.77 | BRD4 (0.51) | LMNABRD4CYP3A4CYP2C9BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |