Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 12/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 10/20 | 0.43 |
| ▸ | BRD2 | P25440 | 8/20 | 0.42 |
| ▸ | BRD3 | Q15059 | 8/20 | 0.42 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | BRD1 | O95696 | 1/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CCL2 | P13500 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | TAF1 | P21675 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16618802 | 0.91 | CYP3A4 (0.47) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL16619324 | 0.90 | CYP3A4 (0.48) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL11909203 | 0.86 | BRD4 (0.55) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL16619338 | 0.86 | BRD4 (0.55) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL16619529 | 0.77 | LMNA (0.55) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL16619532 | 0.77 | LMNA (0.55) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL1907697 | 0.77 | BRD4 (0.57) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL11909184 | 0.76 | BRD4 (0.59) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL16619839 | 0.76 | BRD4 (0.59) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL16618922 | 0.76 | BRD4 (0.49) | BRD4CYP3A4CYP2C9BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |