Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16618826 | 0.85 | CYP1A2 (0.41) | CYP1A2ALDH1A1MAPTCYP2C9CYP2C19 | |
| SCHEMBL16619327 | 0.81 | PDGFRB (0.41) | SMN1; SMN2ALDH1A1MAPTCYP3A4MEN1 | |
| SCHEMBL29970861 | 0.79 | CYP1A2 (0.41) | CYP1A2ALDH1A1MAPTCYP2C9CYP2C19 | |
| SCHEMBL29969235 | 0.79 | CYP1A2 (0.37) | CYP1A2SMN1; SMN2ALDH1A1MAPTCYP2C9 | |
| SCHEMBL26131807 | 0.79 | CYP1A2 (0.41) | CYP1A2ALDH1A1MAPTCYP2C9CYP2C19 | |
| SCHEMBL26131871 | 0.79 | CYP1A2 (0.37) | CYP1A2SMN1; SMN2ALDH1A1MAPTCYP2C9 | |
| SCHEMBL31424455 | 0.75 | PTGES (0.51) | MAPTMEN1KMT2APTGES | |
| SCHEMBL16619984 | 0.74 | PDGFRB (0.44) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL16619219 | 0.74 | ALDH1A1 (0.49) | ALDH1A1MAPTGAA | |
| SCHEMBL16619217 | 0.74 | ALDH1A1 (0.49) | ALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |