Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | PRKDC | P78527 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 12/20 | 0.39 |
| ▸ | BRD2 | P25440 | 8/20 | 0.38 |
| ▸ | BRD3 | Q15059 | 8/20 | 0.38 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 10/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | BRD1 | O95696 | 1/20 | 0.34 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CCL2 | P13500 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | TAF1 | P21675 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11980666 | 0.84 | LMNA (0.48) | LMNAEGFRPRKDCBRD4BRD2 | |
| SCHEMBL16619177 | 0.81 | EGFR (0.45) | EGFRPRKDC | |
| SCHEMBL16619179 | 0.81 | EGFR (0.45) | EGFRPRKDC | |
| SCHEMBL11909184 | 0.81 | BRD4 (0.59) | BRD4BRD2BRD3BRDTCYP3A4 | |
| SCHEMBL16619839 | 0.81 | BRD4 (0.59) | BRD4BRD2BRD3BRDTCYP3A4 | |
| SCHEMBL16618922 | 0.79 | BRD4 (0.49) | LMNABRD4BRD2BRD3BRDT | |
| SCHEMBL16619289 | 0.77 | LMNA (0.59) | LMNAEGFRPRKDCBRD4BRD2 | |
| SCHEMBL16619284 | 0.77 | LMNA (0.59) | LMNAEGFRPRKDCBRD4BRD2 | |
| SCHEMBL18249979 | 0.77 | BRD4 (0.46) | BRD4BRD2BRD3BRDTCYP3A4 | |
| SCHEMBL16619324 | 0.76 | CYP3A4 (0.48) | LMNABRD4BRD2BRD3BRDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |