Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.55 |
| ▸ | BRD4 | O60885 | 7/20 | 0.54 |
| ▸ | BRD2 | P25440 | 5/20 | 0.54 |
| ▸ | BRD3 | Q15059 | 3/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | PRKDC | P78527 | 2/20 | 0.42 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16619284 | 1.00 | LMNA (0.59) | LMNACYP3A4CYP2C9BRD4BRD2 | |
| SCHEMBL16619532 | 0.86 | LMNA (0.55) | LMNACYP3A4CYP2C9BRD4BRD2 | |
| SCHEMBL16619529 | 0.86 | LMNA (0.55) | LMNACYP3A4CYP2C9BRD4BRD2 | |
| SCHEMBL11980666 | 0.85 | LMNA (0.48) | LMNACYP3A4CYP2C9BRD4BRD2 | |
| SCHEMBL16619839 | 0.82 | BRD4 (0.59) | CYP3A4CYP2C9BRD4BRD2BRD3 | |
| SCHEMBL11909184 | 0.82 | BRD4 (0.59) | CYP3A4CYP2C9BRD4BRD2BRD3 | |
| SCHEMBL1904103 | 0.81 | CYP3A4 (0.58) | LMNACYP3A4CYP2C9BRD4BRD2 | |
| SCHEMBL12168779 | 0.80 | CYP3A4 (0.76) | LMNACYP3A4CYP2C9BRD4BRD2 | |
| SCHEMBL16618922 | 0.79 | BRD4 (0.49) | LMNACYP3A4CYP2C9BRD4BRD2 | |
| SCHEMBL16618854 | 0.77 | LMNA (0.42) | LMNACYP3A4CYP2C9BRD4BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |