Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.45 |
| ▸ | PRKDC | P78527 | 5/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.35 |
| ▸ | MAP3K8 | P41279 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.33 |
| ▸ | KRAS | P01116 | 2/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16619179 | 1.00 | EGFR (0.45) | EGFRPRKDCPIK3CAMAP3K8AR | |
| SCHEMBL16619320 | 0.86 | EGFR (0.38) | EGFRPRKDCPIK3CAALDH1A1 | |
| SCHEMBL16619317 | 0.86 | EGFR (0.38) | EGFRPRKDCPIK3CAALDH1A1 | |
| SCHEMBL16619487 | 0.83 | EGFR (0.39) | EGFRPRKDCTNF | |
| SCHEMBL16619390 | 0.82 | EGFR (0.46) | EGFRPRKDCPIK3CAMAP3K8AR | |
| SCHEMBL16619392 | 0.82 | EGFR (0.46) | EGFRPRKDCPIK3CAMAP3K8AR | |
| SCHEMBL16618978 | 0.81 | PRKDC (0.41) | EGFRPRKDCPIK3CATNFATM | |
| SCHEMBL16619383 | 0.81 | PARP1 (0.43) | EGFRPRKDCALDH1A1HPGD | |
| SCHEMBL16618854 | 0.81 | LMNA (0.42) | EGFRPRKDC | |
| SCHEMBL16619646 | 0.79 | EGFR (0.45) | EGFRPRKDCTNFKRASSOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |