SCHEMBL16618871

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16619291	0.92	HTR6 (0.43)	HTR6FGFR4DRD2HTR7
	SCHEMBL16618948	0.91	RORC (0.39)	HTR6RORCKDM2BDRD2HTR7
	SCHEMBL16626655	0.90	RORC (0.39)	HTR6RORCMTNR1AMTNR1B
	Hydrochloric Acid SCHEMBL16618977	0.89	RORC (0.39)	HTR6CNR2RORC
	SCHEMBL16626653	0.88	HTR6 (0.40)	HTR6PPARGDRD2MTNR1AMTNR1B
	SCHEMBL16619196	0.88	HTR6 (0.43)	HTR6MTNR1AMTNR1B
	Hydrochloric Acid SCHEMBL16618792	0.88	HTR6 (0.41)	HTR6PPARGDRD2MTNR1AMTNR1B
	SCHEMBL16619014	0.84	HTR6 (0.37)	HTR6PPARGPPARDPPARACNR2
	SCHEMBL16618717	0.84	HTR6 (0.39)	HTR6PPARGPPARDPPARARORC
	SCHEMBL17971583	0.83	HTR6 (0.36)	HTR6DRD2HTR7MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.