Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24398702 | 0.84 | MEN1 (0.46) | AKR1C3PTGDR2MAPTTDP1MEN1 | |
| SCHEMBL29619095 | 0.84 | MEN1 (0.46) | AKR1C3PTGDR2MAPTTDP1MEN1 | |
| SCHEMBL1903461 | 0.83 | TDP1 (0.48) | AKR1C3PTGS2MAPTTDP1ALDH1A1 | |
| SCHEMBL16619524 | 0.82 | ATAD2 (0.46) | PTGDR2FFAR1POLB | |
| SCHEMBL17467704 | 0.79 | AKR1C3 (0.41) | AKR1C3TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL16619406 | 0.77 | BRD4 (0.44) | CYP2C19 | |
| SCHEMBL1549394 | 0.76 | PTGS2 (0.54) | PTGS2PTGDR2MAPTTDP1MEN1 | |
| SCHEMBL29619010 | 0.76 | MAPT (0.46) | AKR1C3PTGS2MAPTGAATDP1 | |
| SCHEMBL7363912 | 0.76 | PTGS2 (0.57) | PTGS2PTGDR2MAPTGAATDP1 | |
| SCHEMBL5004329 | 0.76 | PTGDR2 (0.77) | PTGS2PTGDR2MAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |