Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 5/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.39 |
| ▸ | BRD2 | P25440 | 3/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16619017 | 0.82 | AKR1C3 (0.47) | PTGDR2FFAR1POLB | |
| SCHEMBL29619075 | 0.81 | BRD4 (0.45) | ATAD2PTGDR2FFAR1BRD4AR | |
| SCHEMBL1907803 | 0.80 | BRD4 (0.48) | ATAD2FFAR1BRD4BRD2BRD3 | |
| SCHEMBL1906132 | 0.80 | BRD4 (0.48) | ATAD2FFAR1BRD4BRD2BRD3 | |
| SCHEMBL16619466 | 0.77 | BRD4 (0.48) | BRD4CYP3A4CYP2C9BRD2BRD3 | |
| SCHEMBL17467705 | 0.76 | MAP4K4 (0.40) | ATAD2HDAC1BRD4ARCYP3A4 | |
| SCHEMBL16619434 | 0.75 | ALDH1A1 (0.42) | FFAR1HDAC1CYP3A4 | |
| SCHEMBL959829 | 0.74 | HTT (0.52) | CYP2C9KDM4EPOLB | |
| SCHEMBL24398370 | 0.73 | BRD4 (0.47) | BRD4BRD2BRD3KDM4E | |
| Hydrochloric Acid SCHEMBL8474144 | 0.72 | ALDH1A1 (0.51) | PTGDR2KDM4EPOLBAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |