Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16619352 | 0.92 | SIRT5 (0.39) | MAPTALDH1A1CYP2C9CYP2C19TP53 | |
| SCHEMBL16619354 | 0.92 | SIRT5 (0.39) | MAPTALDH1A1CYP2C9CYP2C19TP53 | |
| SCHEMBL16619383 | 0.88 | PARP1 (0.43) | MAPTALDH1A1SMN1; SMN2KMT2APARP1 | |
| SCHEMBL16618796 | 0.87 | ALDH1A1 (0.40) | MAPTALDH1A1CYP2C9CYP2C19TP53 | |
| SCHEMBL16618793 | 0.87 | ALDH1A1 (0.40) | MAPTALDH1A1CYP2C9CYP2C19TP53 | |
| SCHEMBL16619317 | 0.83 | EGFR (0.38) | ALDH1A1TP53 | |
| SCHEMBL16619320 | 0.83 | EGFR (0.38) | ALDH1A1TP53 | |
| SCHEMBL16619416 | 0.82 | KDM4E (0.46) | MAPTALDH1A1TP53 | |
| SCHEMBL16619418 | 0.82 | KDM4E (0.46) | MAPTALDH1A1TP53 | |
| SCHEMBL16619217 | 0.80 | ALDH1A1 (0.49) | MAPTALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |