Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16619308 | 0.90 | PDGFRB (0.43) | PDGFRBFGFR1PDGFRAFLT1FGFR3 | |
| SCHEMBL16619327 | 0.76 | PDGFRB (0.41) | PDGFRBPDGFRAMAPTPOLBHTT | |
| SCHEMBL26129153 | 0.74 | HTT (0.46) | PDGFRBFGFR1PDGFRAFLT1FGFR3 | |
| SCHEMBL16619269 | 0.74 | CYP1A2 (0.42) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL16619027 | 0.72 | POLB (0.40) | KDRPOLBALDH1A1EGFRMTNR1A | |
| SCHEMBL20066162 | 0.71 | PDGFRB (0.53) | PDGFRBFGFR1PDGFRAFLT1FGFR3 | |
| SCHEMBL28629349 | 0.71 | SMN1; SMN2 (0.43) | PDGFRBFGFR1PDGFRAFLT1FGFR3 | |
| SCHEMBL16618924 | 0.70 | MAPT (0.36) | MAPTPOLBLMNAALDH1A1MEN1 | |
| SCHEMBL16619278 | 0.70 | MAPT (0.36) | MAPTPOLBLMNAALDH1A1MEN1 | |
| SCHEMBL4634283 | 0.70 | PDGFRB (0.51) | PDGFRBFGFR1PDGFRAFLT1FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |