Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 17/20 | 0.48 |
| ▸ | BRD2 | P25440 | 10/20 | 0.48 |
| ▸ | BRD3 | Q15059 | 10/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11985075 | 0.84 | BRD4 (0.61) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL16619406 | 0.80 | BRD4 (0.44) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL18249909 | 0.78 | BRD4 (0.47) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL16619386 | 0.77 | BRD4 (0.43) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL16619524 | 0.77 | ATAD2 (0.46) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL11980656 | 0.77 | BRD4 (0.51) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL18249987 | 0.75 | NSD3 (0.50) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL18249960 | 0.75 | BRD4 (0.49) | BRD4BRD2BRD3CYP3A4CYP2C9 | |
| SCHEMBL16619017 | 0.74 | AKR1C3 (0.47) | CYP2C19 | |
| SCHEMBL16618802 | 0.72 | CYP3A4 (0.47) | BRD4BRD2BRD3CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |