Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.45 |
| ▸ | PRKDC | P78527 | 3/20 | 0.45 |
| ▸ | TNF | P01375 | 2/20 | 0.41 |
| ▸ | KRAS | P01116 | 2/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 2/20 | 0.37 |
| ▸ | LDHB | P07195 | 2/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16619642 | 1.00 | EGFR (0.45) | EGFRPRKDCTNFKRASSOS1 | |
| SCHEMBL16618743 | 0.85 | EGFR (0.51) | EGFRPRKDCKRASSOS1ALDH1A1 | |
| SCHEMBL16618740 | 0.85 | EGFR (0.51) | EGFRPRKDCKRASSOS1ALDH1A1 | |
| SCHEMBL16619776 | 0.84 | KDM4E (0.47) | EGFRPRKDCTNFLDHALDHB | |
| SCHEMBL16619217 | 0.83 | ALDH1A1 (0.49) | EGFRPRKDCTNFALDH1A1GAA | |
| SCHEMBL16619219 | 0.83 | ALDH1A1 (0.49) | EGFRPRKDCTNFALDH1A1GAA | |
| SCHEMBL16618978 | 0.82 | PRKDC (0.41) | EGFRPRKDCTNFLDHALDHB | |
| SCHEMBL16618852 | 0.81 | EGFR (0.42) | EGFRPRKDCTNFKRASSOS1 | |
| SCHEMBL16618856 | 0.81 | EGFR (0.42) | EGFRPRKDCTNFKRASSOS1 | |
| SCHEMBL16619487 | 0.80 | EGFR (0.39) | EGFRPRKDCTNFLDHALDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |