Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | ROS1 | P08922 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23147255 | 0.84 | MET (0.41) | POLBKMT2APRNPRXFP1EGFR | |
| SCHEMBL16618701 | 0.78 | CYP4F2 (0.42) | ALDH1A1KDM4EGLAHPGDGAA | |
| SCHEMBL16619308 | 0.73 | PDGFRB (0.43) | POLBKMT2AALDH1A1KDM4EGLA | |
| SCHEMBL22122307 | 0.73 | SLC22A12 (0.47) | ALDH1A1KDM4EEGFRMTNR1AMTNR1B | |
| SCHEMBL14756275 | 0.73 | EGFR (0.45) | EGFRKDR | |
| SCHEMBL28816706 | 0.72 | ALOX15 (0.36) | GAAMTNR1AMTNR1B | |
| SCHEMBL16619984 | 0.72 | PDGFRB (0.44) | POLBKMT2AALDH1A1GLAEGFR | |
| SCHEMBL29491487 | 0.71 | FERMT2 (0.48) | POLBKMT2APRNPRXFP1ALDH1A1 | |
| SCHEMBL24010540 | 0.71 | HTR1A (0.56) | ALDH1A1KDM4EGLAHPGDGAA | |
| SCHEMBL22800077 | 0.71 | HSP90AB1 (0.43) | ALDH1A1KDM4EGLAHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |