Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16619984 | 0.90 | PDGFRB (0.44) | PDGFRBFGFR1PDGFRAFLT1FGFR3 | |
| SCHEMBL16618924 | 0.81 | MAPT (0.36) | MAPTPOLBLMNAALDH1A1KDM4E | |
| SCHEMBL15973592 | 0.78 | PDGFRB (0.40) | PDGFRBPDGFRAMAPTPOLBLMNA | |
| SCHEMBL16618826 | 0.76 | CYP1A2 (0.41) | MAPTPOLBALDH1A1KDM4ECTSB | |
| SCHEMBL16618824 | 0.76 | S1PR4 (0.35) | KDRMAPTALDH1A1KDM4EEGFR | |
| SCHEMBL29970057 | 0.76 | PDGFRB (0.43) | PDGFRBPDGFRAMAPTPOLBHTT | |
| SCHEMBL26131542 | 0.76 | PDGFRB (0.43) | PDGFRBPDGFRAMAPTPOLBHTT | |
| SCHEMBL16618995 | 0.75 | ALDH1A1 (0.46) | MAPTPOLBLMNAALDH1A1HPGD | |
| SCHEMBL21099305 | 0.74 | MAPT (0.41) | MAPTHTTLMNAALDH1A1KDM4E | |
| SCHEMBL29970861 | 0.74 | CYP1A2 (0.41) | MAPTPOLBALDH1A1KDM4ECTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |