Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GALR2 | O43603 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16619278 | 0.89 | MAPT (0.36) | MAPTKDM4ETNFALDH1A1TDP1 | |
| SCHEMBL16618995 | 0.81 | ALDH1A1 (0.46) | MAPTALDH1A1TDP1POLBLMNA | |
| SCHEMBL16619308 | 0.81 | PDGFRB (0.43) | MAPTKDM4EALDH1A1TDP1CTSB | |
| SCHEMBL16618701 | 0.76 | CYP4F2 (0.42) | MAPTKDM4ETNFALDH1A1CYP4F2 | |
| SCHEMBL16618826 | 0.76 | CYP1A2 (0.41) | MAPTKDM4EALDH1A1CTSBPOLB | |
| SCHEMBL26131807 | 0.73 | CYP1A2 (0.41) | MAPTKDM4EALDH1A1CTSBPOLB | |
| SCHEMBL29970861 | 0.73 | CYP1A2 (0.41) | MAPTKDM4EALDH1A1CTSBPOLB | |
| SCHEMBL15973592 | 0.73 | PDGFRB (0.40) | MAPTKDM4ETDP1POLBLMNA | |
| SCHEMBL15054971 | 0.71 | HSP90AA1 (0.43) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL25565309 | 0.71 | ALDH1A1 (0.51) | MAPTKDM4ETNFALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |