Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | TK1 | P04183 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28767348 | 0.88 | TK1 (0.44) | LMNATSHRALBTK1PKM | |
| SCHEMBL15285085 | 0.87 | LMNA (0.35) | LMNATSHRALBTK1PKM | |
| SCHEMBL15285061 | 0.87 | PYGM (0.35) | LMNASMN1; SMN2TSHRALBTK1 | |
| SCHEMBL15285039 | 0.87 | TK1 (0.36) | LMNATSHRALBTK1PKM | |
| SCHEMBL34467251 | 0.87 | LMNA (0.39) | LMNASMN1; SMN2TSHRALBTK1 | |
| SCHEMBL8104285 | 0.78 | LMNA (0.41) | LMNASMN1; SMN2TSHRPMP22ESR1 | |
| SCHEMBL30583147 | 0.72 | POLB (0.51) | LMNAALBTK1PKMBLM | |
| SCHEMBL29625276 | 0.71 | POLB (0.53) | TK1 | |
| SCHEMBL30818468 | 0.70 | PDE3A (0.36) | LMNAALBMAPT | |
| SCHEMBL16247014 | 0.69 | TK1 (0.47) | LMNATSHRALBTK1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3105243-A1 | 2',3'-DIDEOXY-5-FLUOROURIDINE DERIVATIVES, A PROCESS FOR THE MANUFACTURE THEREOF AND APPLICATION THEREOF | Adam Mickiewicz University (PL) | 2016-12-21 | — | — | EP | disclosed |
| WO-2015050467-A1 | 2',3'-DIDEOXY-5-FLUOROURIDINE DERIVATIVES, A PROCESS FOR THE MANUFACTURE THEREOF AND APPLICATION THEREOF | ADAM MICKIEWICZ UNIVERSITY (PL) | 2015-04-09 | — | — | WO | disclosed |