Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2579340 | 0.83 | TK1 (0.32) | LMNACYP1A2TSHRPMP22 | |
| SCHEMBL16620134 | 0.78 | LMNA (0.36) | LMNASMN1; SMN2MAPTESR1KDM4E | |
| SCHEMBL25438208 | 0.77 | LMNA (0.43) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL8110184 | 0.77 | LMNA (0.51) | LMNASMN1; SMN2MAPTCYP1A2TSHR | |
| SCHEMBL30841853 | 0.72 | ALDH1A1 (0.41) | LMNATSHRPMP22 | |
| SCHEMBL339966 | 0.72 | ALDH1A1 (0.41) | LMNATSHRPMP22 | |
| SCHEMBL4749295 | 0.72 | PYGM (0.39) | LMNASMN1; SMN2GRIA1GRIA2GRIA4 | |
| SCHEMBL28765909 | 0.71 | LMNA (0.42) | LMNATSHRPMP22 | |
| SCHEMBL2012504 | 0.71 | ALDH1A1 (0.43) | LMNATSHRPMP22 | |
| SCHEMBL8543017 | 0.71 | LMNA (0.47) | LMNASMN1; SMN2MAPTESR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6040297-A | A THERAPEUTIC AGENTS TREATING TUMORS AND RETROVIRAL INFECTIONS INCLUDING HIV INFECTIONS | BIOSEARCH ITALIA, S.P.A. (IT) | 2000-03-21 | — | — | US | disclosed |