Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.36 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7040097 | 0.78 | ALDH1A1 (0.50) | HRH3FAAHALDH1A1HSP90AA1MEN1 | |
| SCHEMBL6553971 | 0.78 | ALDH1A1 (0.50) | HRH3FAAHALDH1A1HSP90AA1MEN1 | |
| SCHEMBL9305130 | 0.74 | GPR84 (0.55) | ALDH1A1EPHX2MEN1KMT2A | |
| SCHEMBL11589563 | 0.69 | ALDH1A1 (0.51) | HRH3FAAHALDH1A1HSP90AA1MEN1 | |
| SCHEMBL28226346 | 0.69 | ALDH1A1 (0.56) | HRH3FAAHALDH1A1HSP90AA1MEN1 | |
| SCHEMBL28316695 | 0.69 | ALDH1A1 (0.56) | HRH3FAAHALDH1A1HSP90AA1MEN1 | |
| SCHEMBL115462 | 0.68 | FAAH (0.53) | HRH3FAAHALDH1A1HSP90AA1MEN1 | |
| SCHEMBL21658583 | 0.68 | ALDH1A1 (0.42) | HRH3FAAHALDH1A1MEN1KMT2A | |
| SCHEMBL16620081 | 0.68 | HSP90AA1 (0.53) | HRH3FAAHALDH1A1HSP90AA1MEN1 | |
| SCHEMBL8513443 | 0.68 | HSP90AA1 (0.53) | HRH3FAAHALDH1A1HSP90AA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057449-A1 | ORGANIC COMPOUNDS | Givaudan S.A. (CH) | 2016-08-24 | — | — | EP | claimed |
| WO-2015050535-A1 | ORGANIC COMPOUNDS | GIVAUDAN S.A. (CH) | 2015-04-09 | — | — | WO | claimed |
| WO-2015049294-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2015-04-09 | — | — | WO | claimed |