Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 4/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.45 |
| ▸ | PPARG | P37231 | 7/20 | 0.45 |
| ▸ | PPARD | Q03181 | 7/20 | 0.45 |
| ▸ | PPARA | Q07869 | 7/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553971 | 1.00 | ALDH1A1 (0.50) | ALDH1A1HSP90AA1FAAHHRH3MEN1 | |
| SCHEMBL9305130 | 0.92 | GPR84 (0.55) | ALDH1A1MEN1KMT2AGPR84PPARG | |
| SCHEMBL7171663 | 0.86 | FAAH (0.46) | ALDH1A1HSP90AA1FAAHHRH3MEN1 | |
| SCHEMBL3230247 | 0.78 | HSP90AA1 (0.53) | ALDH1A1HSP90AA1FAAHHRH3MEN1 | |
| SCHEMBL16620081 | 0.78 | HSP90AA1 (0.53) | ALDH1A1HSP90AA1FAAHHRH3MEN1 | |
| SCHEMBL8513443 | 0.78 | HSP90AA1 (0.53) | ALDH1A1HSP90AA1FAAHHRH3MEN1 | |
| SCHEMBL16620471 | 0.78 | HRH3 (0.45) | ALDH1A1HSP90AA1FAAHHRH3MEN1 | |
| SCHEMBL3902185 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HSP90AA1FAAHHRH3MEN1 | |
| SCHEMBL8511093 | 0.76 | HSP90AA1 (0.52) | ALDH1A1HSP90AA1FAAHHRH3MEN1 | |
| SCHEMBL11589563 | 0.76 | ALDH1A1 (0.51) | ALDH1A1HSP90AA1FAAHHRH3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292566-A2 | PROCESS FOR HYDROLYZING AMIDO-CARBOXYLIC ACID ESTERS INTO AMIDO-CARBOXYLIC ACIDS | EASTMAN CHEMICAL COMPANY (US) | 2003-03-19 | — | — | EP | disclosed |
| US-6497644-B2 | Process for recycling amido-carboxylic acid esters into amino-carboxylic acids | EASTMAN CHEMICAL COMPANY | 2002-12-24 | — | — | US | disclosed |
| US-20020052528-A1 | Process for recycling amido-carboxylic acid esters into amido-carboxylic acids | EASTMAN CHEMICAL COMPANY | 2002-05-02 | — | — | US | disclosed |
| WO-2001092209-A2 | PROCESS FOR HYDROLYZING AMIDO-CARBOXYLIC ACID ESTERS INTO AMIDO-CARBOXYLIC ACIDS | EASTMAN CHEMICAL COMPANY (US) | 2001-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052528-A1 | Process for recycling amido-carboxylic acid esters into amido-carboxylic acids | APEH, NAAA, PARG | ALDH1A1 2053/4885HSP90AA1 1051/4885FAAH 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.