Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29330640 | 0.92 | L3MBTL1 (0.53) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL15497460 | 0.90 | MAPT (0.63) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL16621247 | 0.90 | MEN1 (0.51) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL13955886 | 0.86 | NPC1 (0.58) | MAPTGAAMEN1KMT2ALMNA | |
| SCHEMBL9290196 | 0.84 | MAPT (0.45) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL10995371 | 0.83 | MAPT (0.50) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL13532211 | 0.83 | ALDH1A1 (0.44) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL27612556 | 0.83 | MAPT (0.44) | MAPTALDH1A1GAAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3173764 | 0.81 | ALDH1A1 (0.42) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL11086700 | 0.80 | RAPGEF4 (0.56) | MAPTGAALMNAMAPK1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9997714-B2 | Hole transport material | MERCK PATENT GMBH (DE) | 2018-06-12 | — | — | US | disclosed |
| US-9997714-B2 | Hole transport material | MERCK PATENT GMBH (DE) | 2018-06-12 | — | — | US | disclosed |
| US-9997714-B2 | Hole transport material | MERCK PATENT GMBH (DE) | 2018-06-12 | — | — | US | disclosed |
| US-20160254449-A1 | HOLE TRANSPORT MATERIAL | MERCK PATENT GMBH (DE) | 2016-09-01 | — | — | US | disclosed |
| US-20160254449-A1 | HOLE TRANSPORT MATERIAL | MERCK PATENT GMBH (DE) | 2016-09-01 | — | — | US | disclosed |
| US-20160254449-A1 | HOLE TRANSPORT MATERIAL | MERCK PATENT GMBH (DE) | 2016-09-01 | — | — | US | disclosed |
| EP-3052470-A1 | HOLE TRANSPORT MATERIAL | Merck Patent GmbH (DE) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015049031-A1 | HOLE TRANSPORT MATERIAL | MERCK PATENT GMBH (DE) | 2015-04-09 | — | — | WO | disclosed |
| WO-2015049031-A1 | HOLE TRANSPORT MATERIAL | MERCK PATENT GMBH (DE) | 2015-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160254449-A1 | HOLE TRANSPORT MATERIAL | SUN2, SLC6A19, SLCO2A1 | MAPT 1877/4885ALDH1A1 3172/4885GAA 4349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.