Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | S100A4 | P26447 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9457556 | 0.88 | BCAT2 (0.62) | KMT2ABCAT2CES1CASP1MAPT | |
| SCHEMBL10752700 | 0.83 | ALDH1A1 (0.51) | PTPRCHSP90AA1CDK5CDK5R1NCOA1 | |
| SCHEMBL27958260 | 0.82 | KMT2A (0.58) | PTGS2KMT2ABCAT2ALDH1A1SMN1; SMN2 | |
| SCHEMBL16620979 | 0.82 | KMT2A (0.61) | PTPRCKMT2ABCHEACHECES1 | |
| SCHEMBL7256623 | 0.78 | BCAT2 (0.57) | PTPRCKMT2ABCAT2CES1MAPT | |
| SCHEMBL27924243 | 0.77 | KMT2A (0.55) | KMT2ACASP1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL27906245 | 0.77 | KMT2A (0.55) | KMT2ACASP1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL10448853 | 0.77 | PTGS2 (0.74) | PTPRCHSP90AA1CDK5CDK5R1NCOA1 | |
| SCHEMBL30381875 | 0.76 | CASP1 (0.52) | KMT2ABCAT2CASP1MAPTPARP1 | |
| SCHEMBL28856829 | 0.76 | KMT2A (0.50) | PTPRCHSP90AA1CDK5CDK5R1NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663437-A | 2-(N-benzoylimino)-4, 4-diaminobiphenyl | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1997-09-02 | — | — | US | disclosed |