Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16620066 | 0.76 | PGR (0.45) | — | |
| SCHEMBL14895594 | 0.75 | PDPK1 (0.43) | — | |
| SCHEMBL14895766 | 0.72 | CCR9 (0.36) | — | |
| SCHEMBL20401326 | 0.71 | ACSS2 (0.39) | — | |
| SCHEMBL31617668 | 0.70 | CA12 (0.36) | — | |
| SCHEMBL18113496 | 0.69 | RECQL (0.44) | — | |
| SCHEMBL30554368 | 0.69 | RECQL (0.44) | — | |
| SCHEMBL23901367 | 0.68 | HDAC8 (0.41) | — | |
| SCHEMBL18113677 | 0.68 | NR3C1 (0.32) | — | |
| SCHEMBL29820308 | 0.68 | CYP2A6 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052096-A1 | INHIBITORS OF ERK AND METHODS OF USE | Kura Oncology, Inc. (US) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015051341-A1 | INHIBITORS OF ERK AND METHODS OF USE | ARAXES PHARMA LLC (US) | 2015-04-09 | — | — | WO | disclosed |